Posts

CRISPR Gene editing

Image
INTRODUCTION "Genes are the story and DNA is the language that the story is written in" We live in a time where technology is accelerating exponentially.  The Wright Brothers created the first aircraft back in 1903 and 44 years later Chuck Yeager broke the sound barrier aboard an aircraft. Add 22 years more and there we are, setting our first step on the Moon. These timelines are truly inconceivable. A similar revolution seems to be quietly taking place in this century. About 70 years ago, DNA was first discovered, and within a very short time we have discovered the natural mechanisms which allow us to change the genetic makeup of organisms. This is CRISPR. There have been gene editing technologies in the past , most notably- TALENs (Transcription Activator-Like Effector Nucleases) ZFNs (Zinc Finger Nucleases) Homologous Recombination Base Editing Prime Editing The above have attempted to provide consistent results but their efficacy has not exceeded 50% in most cases. CRISPR...

Life

Image
  we often times tend to not appreciate this thing we call life. It seems as if life needs to have a purpose and it is somehow an unsaid rule we all follow. We get inclined towards things because many a times they seem to resonate with us or just feel “natural” in a way. It is a good thing for sure. The only problem here is , sometimes it becomes such a part of our identity that you start getting defined by those things. Muhammad Ali — The boxer, Newton — the physicist, Elon Musk — the Genius Billionaire Playboy Philanthropist, Arnold — The bodybuilder/Actor. You are identified by “what you do” in this world we live in. The problem lies where the thing you do outgrows you yourself. Sometimes what happens is you grow believing you belong to a certain category and you seem to have your purpose figured out much earlier in life than many people. But, the moment those beliefs are challenged by reality, the world seems meaningless. This thing that you believed is the purpose of life does...